Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.30 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
| ▸ | HTR2C | P28335 | 3/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.30 |
| ▸ | HRH1 | P35367 | 3/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.30 |
| ▸ | HTR2B | P41595 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201595 | 0.78 | L3MBTL1 (0.36) | HDAC1HDAC6ADRA2BADRA2CHTT | |
| SCHEMBL28201579 | 0.77 | HRH1 (0.35) | ADRB2HRH3CHRM2CHRM1DRD2 | |
| SCHEMBL19142282 | 0.72 | CYP11B1 (0.36) | CYP2A6CHRM2CHRM1DRD2HTR2A | |
| SCHEMBL28857380 | 0.70 | HRH1 (0.34) | ADRB2HDAC1HDAC6CHRM2CHRM1 | |
| SCHEMBL4340785 | 0.70 | TSHR (0.32) | HDAC1HDAC6CHRM2CHRM1DRD2 | |
| SCHEMBL28202178 | 0.68 | HDAC8 (0.32) | CHRM2CHRM1DRD2HTR2AHTR2C | |
| SCHEMBL28276888 | 0.68 | CYP11B2 (0.33) | CHRM2CHRM1DRD2HTR2AHTR2C | |
| SCHEMBL28195678 | 0.68 | HDAC1 (0.32) | HDAC1HDAC6CHRM2CHRM1DRD2 | |
| SCHEMBL28201612 | 0.68 | NPC1 (0.33) | CHRM2CHRM1DRD2HTR2AHTR2C | |
| SCHEMBL28201589 | 0.65 | CHRM2 (0.30) | CHRM2CHRM1DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683188-B | The ring pyridinyl derivatives of condensed ring two as FGFR4 inhibitor | 诺华股份有限公司 | 2018-02-09 | — | — | CN | disclosed |