SCHEMBL28205290

SCHEMBL28205290

Nc1ccc(C2C3CC4CC(C3)CC2(c2ccc(N)cc2)C4)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
LMNA P02545 2/20 0.53
PGR P06401 1/20 0.38
POLB P06746 2/20 0.36
ESR1 P03372 1/20 0.33
CYP2C9 P11712 1/20 0.33
ESR2 Q92731 1/20 0.33
CYP19A1 P11511 4/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
GFER P55789 1/20 0.31
KMT2A Q03164 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747207 0.83 ESR2 (0.45) ALDH1A1LMNAPOLBESR1CYP2C9
SCHEMBL2748795 0.83 LIG1 (0.38) ALDH1A1LMNAMEN1KMT2AP2RX7
SCHEMBL5561167 0.79 KDM1A (0.38) ALDH1A1LMNAP2RX7
SCHEMBL2746122 0.78 MEN1 (0.46) ALDH1A1MEN1KMT2AP2RX7
SCHEMBL16088381 0.76 LMNA (0.35) ALDH1A1LMNAPOLBL3MBTL1MEN1
SCHEMBL28270976 0.76 MEN1 (0.31) ALDH1A1LMNAL3MBTL1MEN1GAA
SCHEMBL2747640 0.75 MMP2 (0.38) ALDH1A1LMNAPOLBESR1CYP2C9
SCHEMBL2747175 0.75 MEN1 (0.41) ALDH1A1LMNAPOLBESR1CYP2C9
SCHEMBL2746967 0.75 MEN1 (0.41) ALDH1A1LMNAPOLBESR1CYP2C9
SCHEMBL2747290 0.72 SRD5A2 (0.43) MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843533-A The manufacturing method of optical film 柯尼卡美能达株式会社 2019-06-04 CN disclosed
CN-109563280-A The manufacturing method of polyimide resin film and polyimide resin film 三菱瓦斯化学株式会社 2019-04-02 CN disclosed
CN-108884245-A Polyimide film and method for producing same 柯尼卡美能达株式会社 2018-11-23 CN disclosed
CN-107673977-A A kind of preparation method of the aromatic diamine containing adamantane structure 上海博栋化学科技有限公司 2018-02-09 CN disclosed