Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 4/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | AOC1 | P19801 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205855 | 0.80 | MEN1 (0.60) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL11713041 | 0.78 | MEN1 (0.69) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL28205856 | 0.77 | MEN1 (0.74) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL28343222 | 0.75 | KDM4E (0.49) | MEN1KMT2AMAOAMAOBALDH1A1 | |
| SCHEMBL28346130 | 0.75 | KDM4E (0.46) | MEN1KMT2AMAOAMAOBALDH1A1 | |
| SCHEMBL28481286 | 0.73 | RIPK1 (0.54) | MEN1KMT2AMAOAMAOBALDH1A1 | |
| SCHEMBL6292699 | 0.72 | ESD (0.75) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL28478706 | 0.70 | PTGS1 (0.43) | MEN1KMT2AMAOAMAOBALDH1A1 | |
| SCHEMBL27276997 | 0.69 | MAOB (0.76) | MEN1KMT2AMAOAMAOBAOC1 | |
| SCHEMBL6294304 | 0.68 | MEN1 (0.64) | MEN1KMT2AATMHSP90AA1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | disclosed |