Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775648 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL1557396 | 0.85 | TGM2 (0.54) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL7448378 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL3928127 | 0.81 | LMNA (0.56) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL483306 | 0.81 | TGM2 (0.56) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL14855359 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL645150 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL4291030 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL1415895 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL2295789 | 0.79 | CA12 (0.66) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104302655-B | Sterol derivative and and its for treat involve conversion astroglia disease or treat malignant hematologic disease purposes | 倍塔因诺弗公司 | 2018-04-03 | — | — | CN | disclosed |