Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557396 | 0.86 | TGM2 (0.54) | TGM2CA12CA1CA2CA9 | |
| SCHEMBL8775648 | 0.84 | ALDH1A1 (0.56) | TGM2CA12CA1CA2CA9 | |
| SCHEMBL4493046 | 0.83 | ALDH1A1 (0.57) | TGM2CA12CA1CA2CA9 | |
| SCHEMBL4493048 | 0.83 | ALDH1A1 (0.57) | TGM2CA12CA1CA2CA9 | |
| SCHEMBL7448378 | 0.82 | ALDH1A1 (0.55) | TGM2CA12CA1CA2CA9 | |
| SCHEMBL14855359 | 0.82 | ALDH1A1 (0.55) | TGM2CA12CA1CA2CA9 | |
| SCHEMBL645150 | 0.82 | ALDH1A1 (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3928127 | 0.82 | LMNA (0.56) | TGM2CA12CA1CA2CA9 | |
| SCHEMBL4291030 | 0.81 | ALDH1A1 (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1415895 | 0.81 | ALDH1A1 (0.55) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164554-A | FXR agonist and application thereof | 中国医学科学院药物研究所 | 2023-12-05 | — | — | CN | claimed |
| CN-116396650-A | Ink-absorbing coating | 吉安天晟新材料有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-111171210-A | Tetrafluoroethylene-alkenyl carbamate-perfluoroalkyl vinyl ether dispersion resin and microporous membrane prepared therefrom | 苏州世华新材料科技股份有限公司 | 2020-05-19 | — | — | CN | claimed |
| EP-2952527-B1 | ACRYLATE-STYRENE-ACRYLONITRILE POLYMER AND THERMOPLASTIC RESIN COMPOSITION | LG CHEMICAL LTD (KR) | 2017-05-24 | — | — | EP | claimed |
| US-9637622-B2 | Acrylate-styrene-acrylonitrile polymer and thermoplastic resin composition | LG CHEM, LTD. (KR) | 2017-05-02 | — | — | US | claimed |
| US-20160152806-A1 | ACRYLATE-STYRENE-ACRYLONITRILE POLYMER AND THERMOPLASTIC RESIN COMPOSITION | LG CHEM, LTD. (KR) | 2016-06-02 | — | — | US | claimed |
| EP-2952527-A1 | ACRYLATE-STYRENE-ACRYLONITRILE POLYMER AND THERMOPLASTIC RESIN COMPOSITION | LG Chem, Ltd. (KR) | 2015-12-09 | — | — | EP | claimed |
| CN-105008421-A | Acrylate-styrene-acrylonitrile polymer and thermoplastic resin composition | LG CHEMICAL LTD | 2015-10-28 | — | — | CN | claimed |
| EP-0444482-B1 | Oxetanones | HOFFMANN LA ROCHE (CH) | 1996-01-17 | — | — | EP | claimed |
| US-5260310-A | Oxetanone compounds and pharmaceutical compositions containing them | HOFFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | claimed |
| CN-120289332-A | N-vinyl benzyl carbamate and preparation method thereof | 广安润康药业有限公司 | 2025-07-11 | — | — | CN | disclosed |
| US-12252490-B2 | Inhibiting deubiquitinase USP25 and USP28 | VALO HEALTH, INC. (US) | 2025-03-18 | — | — | US | disclosed |
| WO-2025034745-A1 | 4-AMINOPIPERIDINES AS SELECTIVE MODULATORS OF POTASSIUM CHANNELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-02-13 | — | — | WO | disclosed |
| CN-118307919-A | Composite material of thermoplastic elastomer and polypropylene, and preparation method and application thereof | 石家庄美速体育科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-112823037-B | Inhibition of deubiquitinase USP25 and USP28 | 瓦洛健康股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| WO-2000017164-A1 | 4-CARBOXYAMINO-2-SUBSTITUTED-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-2000017165-A1 | 4-AMINO SUBSTITUTED-2-SUBSTITUTED-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| US-5466708-A | Carbamyloxyoxetanone compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5376674-A | Lipase inhibitors | HOFFMAN-LA ROCHE INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5260310-A | Oxetanone compounds and pharmaceutical compositions containing them | HOFFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12252490-B2 | Inhibiting deubiquitinase USP25 and USP28 | USP28, USP25, USP30 | TGM2 1004/4885CA12 2995/4885CA1 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.