Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905517 | 0.83 | RAB9A (0.45) | MTNR1BMTNR1ASLC2A1RAB9AMAPT | |
| SCHEMBL2817233 | 0.73 | APP (0.62) | RAB9AMAPTAPPGAAALDH1A1 | |
| SCHEMBL22615062 | 0.70 | RAB9A (0.70) | RAB9AMAPTGAAALDH1A1MEN1 | |
| SCHEMBL2815003 | 0.69 | HRH3 (0.39) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL3036905 | 0.69 | TSPO (0.56) | MAPTGAAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10458227 | 0.68 | APP (0.78) | MTNR1BMTNR1ARAB9AMAPTAPP | |
| SCHEMBL19444514 | 0.68 | TSPO (0.56) | ALDH1A1TSPO | |
| SCHEMBL3301661 | 0.68 | APP (0.61) | RAB9AMAPTAPPGAAALDH1A1 | |
| SCHEMBL3627471 | 0.67 | ALDH1A3 (0.51) | RAB9AMAPTAPPGAAALDH1A1 | |
| SCHEMBL14668468 | 0.67 | FYN (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249418-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2213672-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249418-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | APP, APBA1, C1QBP | MTNR1B 1357/4885MTNR1A 1553/4885SLC2A1 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.