Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705078 | 0.88 | KDM4E (0.46) | KDM4EHSD17B10CDC25ACDC25BCES2 | |
| SCHEMBL4694362 | 0.84 | RORC (0.47) | KDM4ECES2CES1TTRCYP2C9 | |
| SCHEMBL2704221 | 0.82 | KMT2A (0.55) | KDM4EHSD17B10ALDH1A1KMT2ARAB9A | |
| SCHEMBL10995760 | 0.79 | KCNMA1 (0.51) | CES2CES1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7118447 | 0.78 | SRD5A2 (0.59) | KDM4EHSD17B10CDC25ACDC25BCES2 | |
| SCHEMBL27678036 | 0.78 | KDM4E (0.43) | KDM4EHSD17B10CDC25ACDC25BCES2 | |
| SCHEMBL6724575 | 0.76 | MAPT (0.56) | KDM4EHSD17B10CES2CES1ALDH1A1 | |
| SCHEMBL8962320 | 0.76 | CDC25B (0.77) | KDM4EHSD17B10CDC25ACDC25BCES2 | |
| SCHEMBL9080711 | 0.75 | KDM4E (0.52) | KDM4EHSD17B10CDC25ACDC25BALDH1A1 | |
| SCHEMBL250099 | 0.75 | CES2 (0.71) | CES2CES1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193750-B | Suppress mitotic Compounds and methods for by suppressing aurora kinase | 千禧药品公司 | 2018-04-27 | — | — | CN | disclosed |