Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215742 | 0.78 | MEN1 (0.41) | MAPT | |
| SCHEMBL28838118 | 0.77 | HTR6 (0.36) | HTR6 | |
| SCHEMBL17207815 | 0.70 | KEAP1 (0.46) | HTR6 | |
| SCHEMBL14818772 | 0.70 | ALDH1A1 (0.44) | MAPTLIMK2 | |
| SCHEMBL28215719 | 0.70 | KDM1A (0.47) | HTR2AHRH1 | |
| SCHEMBL9907231 | 0.69 | TAAR1 (0.42) | TAAR1HTR2AHRH1MALT1 | |
| SCHEMBL28215831 | 0.68 | THRA (0.51) | HTR6MAPTHTR2AHRH1CACNA1B | |
| SCHEMBL12827298 | 0.67 | PSIP1 (0.56) | HTR6TAAR1MAPT | |
| SCHEMBL14803782 | 0.67 | KMT2A (0.49) | METAP2 | |
| SCHEMBL10790182 | 0.65 | CYP3A4 (0.60) | HTR6TAAR1MAPTHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922362-A | 1,3, 4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社钟根堂 | 2018-04-17 | — | — | CN | disclosed |