SCHEMBL28224926

SCHEMBL28224926

NCc1cc(-c2ccc3c(c2-c2ccc(N)c(CN)c2)Cc2ccccc2-3)ccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.52
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PGR P06401 1/20 0.37
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
DPP4 P27487 1/20 0.32
HTR7 P34969 2/20 0.32
HTR2B P41595 2/20 0.32
DRD2 P14416 2/20 0.32
ADRA1D P25100 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28861823 0.99 PNMT (0.51) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL21753909 0.88 PNMT (0.41) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL27636624 0.88 PNMT (0.60) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL29409548 0.81 KDM4E (0.41) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL20483771 0.81 CYP3A4 (0.43) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL25248438 0.81 KDM4E (0.41) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL31046749 0.81 PGR (0.44) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL29409550 0.81 ALDH1A1 (0.42) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL5162291 0.81 ALDH1A1 (0.42) PNMTKDM4ENPC1ALDH1A1LMNA
SCHEMBL7919926 0.81 PGR (0.44) PNMTKDM4ENPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796761-A Display screen component, preparation method and display terminal 努比亚技术有限公司 2019-05-24 CN claimed
CN-110475806-A Polyimides, polyimide solution and Kapton MITSUBISHI GAS CHEMICAL CO 2019-11-19 CN disclosed
CN-110317353-A Include the high molecular optical film of clear polyimides system 住友化学株式会社 2019-10-11 CN disclosed
CN-110234687-A Polyimides mesentery and laminated body 住友化学株式会社 2019-09-13 CN disclosed
CN-110191910-A Polyamideimide resin and optical member comprising the same 住友化学株式会社 2019-08-30 CN disclosed
CN-109791238-A The manufacturing method of optical film and optical film 住友化学株式会社 2019-05-21 CN disclosed
CN-109790308-A Optical film and its manufacturing method 住友化学株式会社 2019-05-21 CN disclosed
CN-109791244-A Optical film and using its stacked film and optical film manufacturing method 住友化学株式会社 2019-05-21 CN disclosed
CN-109721746-A The manufacturing method of resin film 住友化学株式会社 2019-05-07 CN disclosed
CN-109721748-A The manufacturing method of resin film 住友化学株式会社 2019-05-07 CN disclosed
CN-109721747-A The manufacturing method of resin film and the few resin film of small scar 住友化学株式会社 2019-05-07 CN disclosed
CN-109366827-A The manufacturing method of the manufacturing method of transparent resin film and the laminated body with transparent resin film 住友化学株式会社 2019-02-22 CN disclosed
CN-109311287-A Stack membrane 东丽株式会社 2019-02-05 CN disclosed
CN-107443645-B Method for producing transparent resin film and method for producing laminate having transparent resin film 住友化学株式会社 2018-10-16 CN disclosed
CN-108373543-A Polyimide film 住友化学株式会社 2018-08-07 CN disclosed
CN-108307699-A Method for manufacturing insulating layer and multilayer printed circuit board 株式会社LG化学 2018-07-20 CN disclosed