Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474434 | 0.93 | PIN1 (0.53) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| SCHEMBL6903590 | 0.87 | PIN1 (0.47) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| SCHEMBL15945879 | 0.87 | PIN1 (0.47) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| SCHEMBL27546110 | 0.85 | PIN1 (0.46) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| SCHEMBL2761314 | 0.84 | PIN1 (0.51) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| Adipic Acid SCHEMBL27846408 | 0.84 | PIN1 (0.45) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| SCHEMBL15944491 | 0.84 | MMP8 (0.47) | PIN1ALDH1A1RECQLMMP8MEN1 | |
| SCHEMBL27559055 | 0.84 | ALDH1A1 (0.41) | PIN1ALDH1A1MMP8MEN1KMT2A | |
| SCHEMBL2291949 | 0.83 | CYP2C19 (0.47) | ALDH1A1MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL7490885 | 0.83 | ALDH1A1 (0.51) | PIN1ALDH1A1RECQLMMP8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12565493-B2 | Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one | BASF SE (DE) | 2026-03-03 | — | — | US | disclosed |
| US-20240101547-A1 | METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | BASF SE (DE) | 2024-03-28 | — | — | US | disclosed |
| EP-4281441-A1 | METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | BASF SE (DE) | 2023-11-29 | — | — | EP | disclosed |
| EP-2396330-B1 | FUSED PYRIMIDINES | BAYER IP GMBH (DE) | 2016-04-06 | — | — | EP | disclosed |
| US-8614218-B2 | Fused bicyclic pyrimidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-12-24 | — | — | US | disclosed |
| US-7776864-B2 | Fused bicyclic pyrimidines | BAYER SCHERING PHARMA AG (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20100184782-A1 | FUSED BICYCLIC PYRIMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| US-RE41289-E1 | Ultrashort acting hypnotic barbiturates | ARYX THERAPEUTICS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20090137607-A1 | FUSED BICYCLIC PYRIMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20060211759-A1 | Bis-heterocyclic compounds with antitumour and chemosensitising activity | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-09-21 | — | — | US | disclosed |
| EP-0912617-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montell Technology Company bv (NL) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998056833-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-12-17 | — | — | WO | disclosed |
| US-5266702-A | 1,3-oxazoline compounds useful as anionic initiators suitable for polymerization of vinyl polymers | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1993-11-30 | — | — | US | disclosed |
| EP-0267576-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF ALPHA-OLEFINS TO STEREOREGULAR POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION | Himont Incorporated (US) | 1992-05-27 | — | — | EP | disclosed |
| US-4531008-A | Insecticide, miticide | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-07-23 | — | — | US | disclosed |
| US-4266074-A | SUBSTITUTED PHENYL BUTENYL ACETATES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1981-05-05 | — | — | US | disclosed |
| US-4062968-A | MITICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-12-13 | — | — | US | disclosed |
| US-4039680-A | SULFUR CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-08-02 | — | — | US | disclosed |
| US-4031235-A | Insecticidal substituted acetate compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-21 | — | — | US | disclosed |
| US-3996244-A | Insecticidal esters of substituted furan methanol | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211759-A1 | Bis-heterocyclic compounds with antitumour and chemosensitising activity | ABCC1, MCL1, DPYD | PIN1 611/4885ALDH1A1 310/4885RECQL 1056/4885 |
| US-12565493-B2 | Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one | TPMT, UMPS, TST | PIN1 2324/4885ALDH1A1 213/4885RECQL 4050/4885 |
| US-20090137607-A1 | FUSED BICYCLIC PYRIMIDINES | PIK3CA, TYMS, MTOR | PIN1 843/4885ALDH1A1 3182/4885RECQL 867/4885 |
| US-20240101547-A1 | METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | TPMT, TH, UMPS | PIN1 614/4885ALDH1A1 405/4885RECQL 4724/4885 |
| US-20100184782-A1 | FUSED BICYCLIC PYRIMIDINES | PIK3CA, TYMS, MTOR | PIN1 843/4885ALDH1A1 3182/4885RECQL 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.