Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12861364 | 0.79 | OPRM1 (0.45) | ALDH1A1ATMNOTUMLMNASMN1; SMN2 | |
| SCHEMBL9519923 | 0.75 | HTR2A (0.44) | ATMTSHRSIGMAR1 | |
| SCHEMBL6950437 | 0.75 | SIGMAR1 (0.36) | ALDH1A1ATMNOTUMSMN1; SMN2SIGMAR1 | |
| SCHEMBL12203622 | 0.74 | IDH1 (0.44) | ALDH1A1ATMNOTUMHSD17B3IDH1 | |
| Hydrochloric Acid SCHEMBL9518269 | 0.74 | HTR2A (0.43) | ATMTSHRSIGMAR1 | |
| SCHEMBL25787157 | 0.73 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL28424431 | 0.72 | ALDH1A1 (0.40) | ALDH1A1NOTUMLMNASMN1; SMN2 | |
| SCHEMBL9515982 | 0.72 | SLC6A4 (0.39) | SIGMAR1 | |
| SCHEMBL12861363 | 0.72 | ALDH1A1 (0.41) | ALDH1A1NOTUMSMN1; SMN2 | |
| SCHEMBL9527366 | 0.71 | ATM (0.42) | ATMNOTUMSMN1; SMN2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484481-A | A kind of synthetic method of the spiro-compound of dihydro -1H- indenes | 遵义医学院 | 2018-09-04 | — | — | CN | disclosed |