Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 5/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645205 | 0.88 | HTR6 (0.55) | HTR6FEN1PARP1 | |
| SCHEMBL28233724 | 0.84 | BTK (0.37) | KDM4CKDM5AKDM5BBTK | |
| SCHEMBL28076562 | 0.80 | CALCRL (0.40) | PARP1 | |
| SCHEMBL28076558 | 0.80 | CALCRL (0.40) | PARP1 | |
| SCHEMBL18285521 | 0.76 | OPRM1 (0.40) | KDM4EMAPK1ALDH1A1BTK | |
| SCHEMBL18285527 | 0.76 | OPRM1 (0.40) | KDM4EMAPK1ALDH1A1BTK | |
| SCHEMBL28484312 | 0.76 | HRH3 (0.42) | KDM4EALDH1A1BTK | |
| SCHEMBL15155889 | 0.75 | EGFR (0.39) | KDM4EMAPK1LCKBTKKMT2A | |
| SCHEMBL2569345 | 0.74 | TLR7 (0.46) | HTR6KDM4EMAPK1ALDH1A1KMT2A | |
| SCHEMBL18645213 | 0.74 | HTR6 (0.47) | HTR6PARP1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753863-B | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105753863-A | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2016-07-13 | — | — | CN | disclosed |