Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18733356 | 0.82 | LMNA (0.33) | PTGS2PTGS1TP53L3MBTL1PDE4B | |
| SCHEMBL2523217 | 0.77 | RAB9A (0.39) | PTGS2PTGS1KDM4ELMNACYP3A4 | |
| SCHEMBL18695205 | 0.76 | TP53 (0.41) | PTGS2PTGS1TP53L3MBTL1PDE4B | |
| SCHEMBL18467787 | 0.74 | TP53 (0.41) | PTGS2PTGS1TP53L3MBTL1KDM4E | |
| SCHEMBL18695253 | 0.73 | TP53 (0.45) | TP53L3MBTL1KDM4ELMNACYP1A2 | |
| SCHEMBL25212516 | 0.72 | TGFBR1 (0.33) | PTGS2PTGS1KDM4ELMNACYP3A4 | |
| SCHEMBL31532384 | 0.72 | LMNA (0.40) | PTGS2PTGS1TP53L3MBTL1KDM4E | |
| SCHEMBL18695186 | 0.71 | L3MBTL1 (0.43) | TP53L3MBTL1PDE4BKDM4ELMNA | |
| SCHEMBL27783208 | 0.68 | LMNA (0.40) | TP53L3MBTL1KDM4ELMNA | |
| SCHEMBL28957484 | 0.67 | PTGS1 (0.58) | PTGS2PTGS1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473480-A | The oxinane sulfone of pyrazolyl substitution | 格吕伦塔尔有限公司 | 2018-08-31 | — | — | CN | disclosed |