Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793545 | 0.82 | VCP (0.50) | NFE2L2VCPMGAMALDH1A1TRPA1 | |
| SCHEMBL1547756 | 0.78 | NFE2L2 (0.56) | NFE2L2TUBB1ALDH1A1TRPA1 | |
| SCHEMBL4798296 | 0.78 | NPFFR1 (0.44) | TUBB1ALDH1A1TRPA1 | |
| SCHEMBL16960237 | 0.77 | KDM1A (0.37) | KDM1AKCNH2KDM1BRCOR1NFE2L2 | |
| SCHEMBL29620495 | 0.77 | ALDH1A1 (0.43) | KDM1AKCNH2KDM1BRCOR1NFE2L2 | |
| SCHEMBL361060 | 0.77 | ALDH1A1 (0.50) | KDM1AKCNH2KDM1BVCPMGAM | |
| SCHEMBL1506429 | 0.77 | ALDH1A1 (0.43) | KDM1AKCNH2KDM1BRCOR1NFE2L2 | |
| SCHEMBL24666526 | 0.77 | MGAM (0.40) | KDM1AKCNH2KDM1BRCOR1NFE2L2 | |
| SCHEMBL10871325 | 0.74 | ALDH1A1 (0.50) | TUBB1ALDH1A1 | |
| SCHEMBL30834416 | 0.74 | TRPA1 (0.44) | MGAMGAASIMGAM2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263929-B | 3-Pyrimidin-4-yl-oxazolidin-2-one compounds as mutant IDH inhibitors | 诺华股份有限公司 | 2018-08-28 | — | — | CN | disclosed |