SCHEMBL361060

SCHEMBL361060

O=Cc1ccc(Br)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A3 P47895 2/20 0.43
KDM4E B2RXH2 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH3A1 P30838 1/20 0.41
KIF11 P52732 1/20 0.39
CYP2A6 P11509 1/20 0.39
VCP P55072 1/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM1A O60341 2/20 0.37
KCNH2 Q12809 2/20 0.37
KDM1B Q8NB78 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6070467 0.86 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2ALDH1A3KDM4EPTGS2
SCHEMBL6070471 0.86 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2ALDH1A3KDM4EPTGS2
SCHEMBL29527566 0.82 VCP (0.55) ALDH1A1SMN1; SMN2ALDH1A3KDM4EPTGS2
SCHEMBL154905 0.82 VCP (0.55) ALDH1A1SMN1; SMN2ALDH1A3KDM4EPTGS2
SCHEMBL21838841 0.82 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2RAB9ATSHRMEN1
SCHEMBL21676224 0.79 XDH (0.48) ALDH1A1KDM4EVCPKDM1AKCNH2
SCHEMBL31335285 0.79 XDH (0.48) ALDH1A1KDM4EVCPKDM1AKCNH2
SCHEMBL870202 0.78 ALDH1A3 (0.52) ALDH1A1ALDH1A3KDM4EPTGS2RAB9A
SCHEMBL48607 0.78 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2KDM4EPTGS2RAB9A
SCHEMBL29389102 0.78 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2KDM4EPTGS2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228475-A1 PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL)METHYL)BENZYL)AMINO)ISOINDOLINE-1,3-DIONE CELGENE CORPORATION 2024-07-11 US claimed
EP-4359380-A1 PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE Celgene Corporation (US) 2024-05-01 EP claimed
CN-117425642-A Preparation method of (S) -2- (2, 6-dioxopiperidine-3-yl) -4- ((2-fluoro-4- ((3-morpholinoazetidin-1-yl) methyl) benzyl) amino) isoindoline-1, 3-dione 新基公司 2024-01-19 CN claimed
WO-2022271557-A1 PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE CELGENE CORPORATION (US) 2022-12-29 WO claimed
CN-113548982-B Preparation method of 4-cyano-2-fluorobenzyl alcohol 上海三牧化工技术有限公司 2022-05-06 CN claimed
CN-113548982-A Preparation method of 4-cyano-2-fluorobenzyl alcohol 上海三牧化工技术有限公司 2021-10-26 CN claimed
US-10017684-B2 Method and compositions for hydraulic fracturing and for tracing formation water SPECTRUM TRACER SERVICES, LLC (US) 2018-07-10 US claimed
US-20170306217-A1 METHOD AND COMPOSITIONS FOR HYDRAULIC FRACTURING AND FOR TRACING FORMATION WATER NCS Multistage, LLC 2017-10-26 US claimed
US-12612360-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof SANOFI (FR) 2026-04-28 US disclosed
EP-4729059-A2 THIAZOLO [5,4-B] PYRIDINE MALT-1 INHIBITORS Abbvie Inc. (US) 2026-04-22 EP disclosed
US-12606533-B2 3-phenylpropylamine derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 US disclosed
EP-4719605-A1 CHEMICAL COMPOUNDS AND USES THEREOF GlaxoSmithKline Intellectual Property (No.4) Limited (GB) 2026-04-08 EP disclosed
US-20260085034-A1 N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2026-03-26 US disclosed
EP-4713319-A1 SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-03-25 EP disclosed
US-5238599-A Low threshold voltage, low driving voltage SEIKO EPSON CORPORATION (JP) 1993-08-24 US disclosed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
US-5061726-A Alkynylphenyl-substituted 1,3-oxathione compounds with pesticidal activity THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-10-29 US disclosed
EP-0400861-A1 1,3-dioxane derivative and liquid crystal composition incorporating the same SEIKO EPSON CORPORATION (JP) 1990-12-05 EP disclosed
CN-1045576-A Pesticide WELLCOME FOUND (GB) 1990-09-26 CN disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612360-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof ESRRA, FSHR, GPER1 ALDH1A1 1356/4885SMN1; SMN2 3940/4885ALDH1A3 3061/4885
US-12606533-B2 3-phenylpropylamine derivative SF3A1, SF1, HTR1D ALDH1A1 357/4885SMN1; SMN2 707/4885ALDH1A3 1680/4885
US-20240228475-A1 PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL)METHYL)BENZYL)AMINO)ISOINDOLINE-1,3-DIONE AQP1, AQP3, ADH1C ALDH1A1 749/4885SMN1; SMN2 738/4885ALDH1A3 2817/4885
US-20260085034-A1 N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF GYS2, GYS1, PYGL ALDH1A1 2396/4885SMN1; SMN2 397/4885ALDH1A3 3206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.