SCHEMBL28243729

SCHEMBL28243729

CC(C)c1cccc2c([Na])ccc-2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
HDAC4 P56524 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MDM4 O15151 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
TYR P14679 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CA5A P35218 1/20 0.39
HTT P42858 1/20 0.39
MDM2 Q00987 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9177215 0.79 RXRA (0.50) RXRARXRBRXRGHDAC4HDAC8
SCHEMBL9875662 0.78 LMNA (0.55) RXRARXRBRXRGHDAC4HDAC8
SCHEMBL9876285 0.78 RXRA (0.46) RXRARXRBRXRGHDAC4HDAC8
SCHEMBL9875654 0.77 RXRA (0.53) RXRARXRBRXRGHDAC4HDAC8
SCHEMBL9876152 0.74 RXRA (0.46) RXRARXRBRXRGMAPTALDH1A1
SCHEMBL9874684 0.74 ATM (0.44) RXRARXRBRXRGHDAC4HDAC8
SCHEMBL9618739 0.74 RXRA (0.46) RXRARXRBRXRGHDAC4HDAC8
SCHEMBL5352034 0.74 RXRA (0.62) RXRARXRBRXRGHDAC4HDAC8
SCHEMBL11423533 0.73 HTR7 (0.49) RXRARXRBRXRGBRD4CREBBP
SCHEMBL29727254 0.73 TRPA1 (0.46) RXRARXRBRXRGHDAC4HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108451825-A A kind of skin conditioning composition after depilation and application 佛山云裳化妆品有限公司 2018-08-28 CN disclosed