Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962436 | 0.91 | IDO1 (0.47) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL4202389 | 0.81 | TSHR (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL29577269 | 0.81 | TSHR (0.44) | POLBAPEX1HTTTDP1ELANE | |
| Benzoic Acid SCHEMBL29186308 | 0.80 | TDP1 (0.53) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL8988143 | 0.79 | IAPP (0.50) | TSHRCYBB | |
| SCHEMBL7077409 | 0.79 | HTT (0.48) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL28186367 | 0.78 | L3MBTL1 (0.51) | POLBAPEX1HTTTDP1ELANE | |
| Benzoic Acid SCHEMBL28244407 | 0.78 | CA12 (0.46) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL31707533 | 0.77 | ALDH1A1 (0.52) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL1372181 | 0.77 | THRB (0.42) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108603953-A | Light diffusing agent, light-diffusing resin composition and formed body | 三菱瓦斯化学株式会社 | 2018-09-28 | — | — | CN | disclosed |