Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RPA1 | P27694 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083293 | 0.79 | XDH (0.42) | MAPTL3MBTL1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL28284102 | 0.78 | LMNA (0.41) | MAPTL3MBTL1MAPK1ALDH1A1GAA | |
| SCHEMBL28395393 | 0.78 | MAPT (0.57) | MAPTL3MBTL1MAPK1ALDH1A1GAA | |
| SCHEMBL28226658 | 0.78 | PTGS2 (0.54) | MAPTL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7489890 | 0.78 | KDR (0.40) | MAPTALDH1A1GAAHTTLMNA | |
| SCHEMBL28226587 | 0.78 | LMNA (0.41) | MAPTL3MBTL1MAPK1RECQLALDH1A1 | |
| SCHEMBL244194 | 0.77 | MAPK1 (0.56) | MAPTL3MBTL1MAPK1ALDH1A1GAA | |
| SCHEMBL31457162 | 0.76 | ALDH1A1 (0.63) | MAPTL3MBTL1MAPK1RECQLALDH1A1 | |
| SCHEMBL10384028 | 0.76 | ALDH1A1 (0.63) | MAPTL3MBTL1MAPK1RECQLALDH1A1 | |
| SCHEMBL20386583 | 0.76 | L3MBTL1 (0.49) | MAPTL3MBTL1MAPK1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829538-B | Pyrazole compound containing chrysanthemic acid structure, preparation method and application | 南京工业大学 | 2018-10-16 | — | — | CN | disclosed |