SCHEMBL28256993

SCHEMBL28256993

CCCC(=O)C(O)(CCC)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.40
HDAC1 Q13547 4/20 0.40
HDAC2 Q92769 4/20 0.40
HDAC8 Q9BY41 4/20 0.40
FFAR3 O14843 3/20 0.40
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33
CYP2C19 P33261 1/20 0.33
FDPS P14324 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
FAAH O00519 1/20 0.31
AKR1B1 P15121 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31476971 0.85 AKR1B1 (0.41) ALDH1A1TSHRMEN1KMT2AFAAH
SCHEMBL28409611 0.84 FAAH (0.52) CES2CES1ALDH1A1TSHRMEN1
SCHEMBL1704637 0.83 ALDH1A1 (0.40) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL7514935 0.80 HDAC3 (0.39) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL2776898 0.80 FDPS (0.35) ALDH1A1TSHRFDPSMEN1CYP1A2
SCHEMBL8418815 0.80 FFAR3 (0.44) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL29011393 0.78 FDPS (0.37) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL25176594 0.75 FAAH (0.52) CES2CES1ALDH1A1TSHRMEN1
Oxalic Acid SCHEMBL2876245 0.75 FDPS (0.32) FDPS
SCHEMBL9219405 0.75 FAAH (0.52) CES2CES1ALDH1A1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108852894-A It is a kind of for repairing the polypeptides in combination of whitening wrinkle-removing 浙江湃肽生物有限公司 2018-11-23 CN claimed
CN-114836488-B Anti-wrinkle repair composition containing polypeptide and preparation method thereof 浙江湃肽生物股份有限公司 2023-02-17 CN disclosed
CN-114869796-A Whitening and skin-brightening repair composition containing active polypeptide and application thereof 浙江湃肽生物股份有限公司 2022-08-09 CN disclosed
CN-114836488-A Anti-wrinkle repair composition containing polypeptide and preparation method thereof 浙江湃肽生物股份有限公司 2022-08-02 CN disclosed
CN-108852894-A It is a kind of for repairing the polypeptides in combination of whitening wrinkle-removing 浙江湃肽生物有限公司 2018-11-23 CN disclosed