SCHEMBL2776898

SCHEMBL2776898

CCCC(O)(C(=O)O)C(=O)CN

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.35
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL2876245 0.94 FDPS (0.32) FDPS
SCHEMBL458918 0.82 GLRA1 (0.35) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL1704637 0.81 ALDH1A1 (0.40) FDPSALDH1A1MEN1CYP1A2THRB
Ammonia Solution, Strong SCHEMBL7868700 0.80 ALDH1A1 (0.33) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL28256993 0.80 HDAC3 (0.40) FDPSALDH1A1MEN1CYP1A2THRB
Oxalic Acid SCHEMBL4385511 0.77 MEN1 (0.31) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL29011393 0.77 FDPS (0.37) FDPSALDH1A1MEN1CYP1A2THRB
SCHEMBL28409611 0.74 FAAH (0.52) ALDH1A1MEN1CYP1A2KMT2AOR51E2
SCHEMBL27705640 0.72 MEN1 (0.35) FDPSALDH1A1MEN1CYP1A2THRB
SCHEMBL7514935 0.70 HDAC3 (0.39) ALDH1A1MEN1CYP1A2THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2613810-B9 BIODEGRADABLE, WATER SOLUBLE AND PH RESPONSIVE POLY(ORGANO)PHOSPHAZENES JOHANNES KEPLER UNIVERSITÄT LINZ (AT) 2016-02-17 EP claimed
US-9192677-B2 Biodegradable, water soluble and pH responsive poly(organo)phosphazenes JOHANNES KEPLER UNIVERSITÄT LINZ (AT) 2015-11-24 US claimed
EP-2613810-B1 BIODEGRADABLE, WATER SOLUBLE AND PH RESPONSIVE POLY(ORGANO)PHOSPHAZENES JOHANNES KEPLER UNIVERSITÄT LINZ (AT) 2015-07-15 EP claimed
US-20130324490-A1 BIODEGRADABLE, WATER SOLUBLE AND PH RESPONSIVE POLY(ORGANO)PHOSPHAZENES JOHANNES KEPLER UNIVERSITÄT LINZ (AT) 2013-12-05 US claimed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US claimed
EP-2155806-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF Korea Institute of Science and Technology (KR) 2010-02-24 EP claimed
WO-2008153278-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-18 WO claimed
US-12168719-B2 Composition of thermosensitive hydrogels having altered reversible sol-gel transition property, and use thereof Nexgel Biotech Co. Ltd (KR) 2024-12-17 US disclosed
EP-4067435-A1 TEMPERATURE-SENSITIVE HYDROGEL COMPOSITION HAVING CHANGED REVERSIBLE SOL-GEL TRANSITION PROPERTY AND USE THEREOF Korea Institute of Science and Technology (KR) 2022-10-05 EP disclosed
US-11261271-B2 Thermosensitive phosphazene-based polymer comprising sulfate moiety, and preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2022-03-01 US disclosed
WO-2021107298-A1 TEMPERATURE-SENSITIVE HYDROGEL COMPOSITION HAVING CHANGED REVERSIBLE SOL-GEL TRANSITION PROPERTY AND USE THEREOF 한국과학기술연구원 2021-06-03 WO disclosed
US-20210163691-A1 COMPOSITION OF THERMOSENSITIVE HYDROGELS HAVING ALTERED REVERSIBLE SOL-GEL TRANSITION PROPERTY, AND USE THEREOF NEXGEL BIOTECH CO., LTD (KR) 2021-06-03 US disclosed
US-20200048377-A1 Thermosensitive phosphazene-based polymer comrising sulfonated moiety, and preparation method and use thereof NEXGEL BIOTECH CO., LTD (KR) 2020-02-13 US disclosed
EP-1654302-A1 THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2006-05-10 EP disclosed
WO-2005010079-A1 THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-02-03 WO disclosed
US-20050020808-A1 Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-01-27 US disclosed
EP-1161480-B1 BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD KOREA INST SCI & TECH (KR) 2004-12-22 EP disclosed
EP-1161480-A1 BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-12-12 EP disclosed
US-6319984-B1 TEMPERATURE-SENSITIVITY AND BIODEGRADABILITY CAN BE CONTROLLED AS DESIRED BY SUBSTITUTING POLYDICHLOROPHOSPHAZENE WITH METHOXY HEPTA(ETHYLENE GLYCOL), DEPSIPEPTIDES AND AMINO ACID ESTERS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-11-20 US disclosed
WO-2001036516-A1 BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130324490-A1 BIODEGRADABLE, WATER SOLUBLE AND PH RESPONSIVE POLY(ORGANO)PHOSPHAZENES PHOSPHO1, PTEN, ALK FDPS 1484/4885ALDH1A1 3412/4885MEN1 634/4885
US-20050020808-A1 Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same PHOSPHO1, INPPL1, PLCG1 FDPS 286/4885ALDH1A1 3295/4885MEN1 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.