Oxalic Acid

Oxalic Acid

SCHEMBL2876245

CCCC(O)(C(=O)O)C(=O)CN.N.O=C(O)C(=O)O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.32
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776898 0.94 FDPS (0.35) FDPS
Oxalic Acid SCHEMBL4385511 0.84 MEN1 (0.31)
Ammonia Solution, Strong SCHEMBL7868700 0.79 ALDH1A1 (0.33)
SCHEMBL458918 0.77 GLRA1 (0.35)
SCHEMBL1704637 0.76 ALDH1A1 (0.40) FDPS
SCHEMBL28256993 0.75 HDAC3 (0.40) FDPS
SCHEMBL29011393 0.72 FDPS (0.37) FDPS
SCHEMBL9507919 0.69 TET2 (0.38) FDPS
SCHEMBL28409611 0.69 FAAH (0.52) ALOX15
SCHEMBL27705640 0.68 MEN1 (0.35) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11261271-B2 Thermosensitive phosphazene-based polymer comprising sulfate moiety, and preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2022-03-01 US disclosed
WO-2021107298-A1 TEMPERATURE-SENSITIVE HYDROGEL COMPOSITION HAVING CHANGED REVERSIBLE SOL-GEL TRANSITION PROPERTY AND USE THEREOF 한국과학기술연구원 2021-06-03 WO disclosed
US-20210163691-A1 COMPOSITION OF THERMOSENSITIVE HYDROGELS HAVING ALTERED REVERSIBLE SOL-GEL TRANSITION PROPERTY, AND USE THEREOF NEXGEL BIOTECH CO., LTD (KR) 2021-06-03 US disclosed
US-20200048377-A1 Thermosensitive phosphazene-based polymer comrising sulfonated moiety, and preparation method and use thereof NEXGEL BIOTECH CO., LTD (KR) 2020-02-13 US disclosed
EP-1981544-B1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF KIST KOREA INSTITUTE OF SCIENCE AND TECH (KR) 2019-06-19 EP disclosed
US-9526699-B2 Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof KIST (KR) 2016-12-27 US disclosed
EP-1654302-B1 THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME KOREA INST SCI & TECH (KR) 2014-09-17 EP disclosed
CN-101360513-B Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof KOREA INST SCI & TECH 2013-01-23 CN disclosed
EP-2540764-A2 Poly(organophosphazene) composition for biomaterials Korea Institute of Science and Technology (KR) 2013-01-02 EP disclosed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US disclosed
US-20090022683-A1 Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof KIST (KR) 2009-01-22 US disclosed
WO-2008153277-A1 POLY(ORGANOPHOSPHAZENE) HYDROGELS FOR DRUG DELIVERY, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-18 WO disclosed
US-7259225-B2 Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-08-21 US disclosed
EP-1654302-A1 THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2006-05-10 EP disclosed
WO-2005010079-A1 THERMOSENSITIVE POLY (ORGANOPHOSPHAZENES), PREPARATION METHOD THEREOF AND INJECTABLE THERMOSENSITIVE POLYPHOSPHAZENE HYDROGELS USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-02-03 WO disclosed
US-20050020808-A1 Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-01-27 US disclosed
EP-1161480-B1 BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD KOREA INST SCI & TECH (KR) 2004-12-22 EP disclosed
EP-1161480-A1 BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-12-12 EP disclosed
US-6319984-B1 TEMPERATURE-SENSITIVITY AND BIODEGRADABILITY CAN BE CONTROLLED AS DESIRED BY SUBSTITUTING POLYDICHLOROPHOSPHAZENE WITH METHOXY HEPTA(ETHYLENE GLYCOL), DEPSIPEPTIDES AND AMINO ACID ESTERS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-11-20 US disclosed
WO-2001036516-A1 BIODEGRADABLE AND THERMOSENSITIVE POLYPHOSPHAZENES AND THEIR PREPARATION METHOD KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090022683-A1 Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof PHOSPHO1, PGLS, LIPE FDPS 1272/4885ALOX15 3157/4885
US-20050020808-A1 Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same PHOSPHO1, INPPL1, PLCG1 FDPS 286/4885ALOX15 2752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.