Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255446 | 0.87 | CHRNB2 (0.60) | CHRNB2CHRNA4HTR7HTR1AADRB1 | |
| Tert-Butyl Formate SCHEMBL27934064 | 0.86 | HTR1A (0.45) | CHRNB2CHRNA4HTR7HTR1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL2869885 | 0.86 | CHRNB2 (0.58) | CHRNB2CHRNA4HTR7HTR1AADRB1 | |
| Tert-Butyl Formate SCHEMBL27945517 | 0.83 | MAPT (0.45) | HTR7HTR1AALDH1A1ADRB1HTR3E | |
| Tert-Butyl Formate SCHEMBL27809028 | 0.83 | HTR3E (0.43) | HTR7HTR1AALDH1A1ADRB1HTR3E | |
| Tert-Butyl Formate SCHEMBL27945498 | 0.81 | MAPT (0.43) | CHRNB2CHRNA4HTR7HTR1AALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28258248 | 0.81 | ADRB1 (0.39) | CHRNB2CHRNA4HTR7HTR1AADRB1 | |
| Tert-Butyl Formate SCHEMBL27859337 | 0.80 | ADRB1 (0.47) | CHRNB2CHRNA4ALDH1A1ADRB1HTR3E | |
| Tert-Butyl Formate SCHEMBL27824904 | 0.79 | ADRB1 (0.50) | HTR7HTR1AALDH1A1ADRB1HTR3E | |
| Tert-Butyl Formate SCHEMBL28840344 | 0.78 | HTR6 (0.48) | HTR7ALDH1A1ADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |