Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 5/20 | 0.42 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957578 | 0.84 | ACACB (0.42) | DRD2USP25USP28NQO2FAAH | |
| SCHEMBL29707354 | 0.83 | FAAH (0.46) | DRD2IDO1USP25NQO2FAAH | |
| SCHEMBL22957491 | 0.83 | FAAH (0.46) | DRD2IDO1USP25NQO2FAAH | |
| SCHEMBL22957300 | 0.81 | NAMPT (0.51) | USP25USP28FAAH | |
| SCHEMBL19212187 | 0.80 | SIGMAR1 (0.46) | DRD2TMEM97MAPT | |
| SCHEMBL6679588 | 0.76 | NQO2 (0.48) | DRD2IDO1NQO2MAPT | |
| SCHEMBL28350815 | 0.74 | MAPT (0.49) | DRD2IDO1NQO2MAPT | |
| SCHEMBL28258183 | 0.74 | FAAH (0.42) | USP25USP28TMEM97NQO2FAAH | |
| SCHEMBL24120598 | 0.74 | SMN1; SMN2 (0.52) | MAPTTLR7 | |
| SCHEMBL8419482 | 0.73 | MTNR1A (0.67) | DRD2IDO1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |