Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTR5A | P47898 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28258434 | 0.84 | ACHE (0.52) | ALDH1A1KMT2AHTR2CHTR2BKDM4E | |
| Hydrochloric Acid SCHEMBL28256811 | 0.80 | HTR5A (0.38) | LMNAHTR5AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL20683408 | 0.79 | ARG1 (0.50) | ALDH1A1KMT2ALMNAHTR5AADRB2 | |
| SCHEMBL28256884 | 0.78 | ABL1 (0.37) | ALDH1A1KDM4EABL1RIN1 | |
| SCHEMBL28258397 | 0.78 | ABL1 (0.60) | BCHEABL1RIN1 | |
| SCHEMBL28258433 | 0.76 | ACHE (0.52) | KMT2AMEN1ABL1RIN1POLB | |
| SCHEMBL28256885 | 0.76 | CCR8 (0.39) | ALDH1A1KDM4EABL1RIN1 | |
| SCHEMBL894216 | 0.75 | ARG1 (0.65) | ALDH1A1KMT2A | |
| SCHEMBL28258406 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2ALMNAHTR5AADRB2 | |
| Hydrochloric Acid SCHEMBL895235 | 0.74 | ARG1 (0.64) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876955-B | Arginase inhibitor and its treatment use | 马尔斯公司 | 2018-11-23 | — | — | CN | disclosed |