Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | MMP12 | P39900 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898281 | 0.76 | CYP4F2 (0.49) | SMN1; SMN2POLBNPC1RECQLRAB9A | |
| SCHEMBL28263155 | 0.74 | RIPK1 (0.42) | SMN1; SMN2POLBNPC1RECQLRAB9A | |
| SCHEMBL27611273 | 0.71 | NPC1 (0.63) | SMN1; SMN2POLBNPC1RECQLRAB9A | |
| SCHEMBL29278320 | 0.68 | NPC1 (0.57) | SMN1; SMN2NPC1RECQLRAB9AMAPT | |
| SCHEMBL28848147 | 0.68 | TYR (0.51) | NPC1RAB9APKMMAPTTSHR | |
| SCHEMBL30898252 | 0.68 | CYP4F2 (0.48) | ALDH1A1SMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL8703426 | 0.67 | TDP1 (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL28497792 | 0.67 | LMNA (0.45) | SMN1; SMN2HPGDPKMCYP2C9LMNA | |
| SCHEMBL27741038 | 0.67 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL27796948 | 0.67 | RIPK1 (0.43) | ALDH1A1POLBNPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111383-A | The diphenyl sulfide derivative and application thereof that 2- replaces | 广东东阳光药业有限公司 | 2019-01-01 | — | — | CN | disclosed |