Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796948 | 0.92 | RIPK1 (0.43) | RIPK1TAAR1RAB9ANPC1ANO1 | |
| SCHEMBL30898281 | 0.84 | CYP4F2 (0.49) | RAB9ANPC1RECQLSMN1; SMN2POLB | |
| SCHEMBL27629113 | 0.82 | KMT2A (0.50) | RIPK1RAB9ANPC1ANO1KMT2A | |
| SCHEMBL27611273 | 0.80 | NPC1 (0.63) | RAB9ANPC1RECQLSMN1; SMN2POLB | |
| SCHEMBL6632237 | 0.79 | RAD52 (0.46) | TAAR1RAB9AKMT2APOLBMAPT | |
| SCHEMBL2545484 | 0.76 | LMNA (0.60) | TAAR1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL29278320 | 0.75 | NPC1 (0.57) | RAB9ANPC1RECQLSMN1; SMN2MAPT | |
| SCHEMBL28848147 | 0.75 | TYR (0.51) | TAAR1RAB9ANPC1ANO1MAPT | |
| SCHEMBL30898252 | 0.75 | CYP4F2 (0.48) | RAB9ANPC1RECQLSMN1; SMN2MAPT | |
| SCHEMBL28263115 | 0.74 | ALDH1A1 (0.34) | RAB9ANPC1RECQLSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111383-A | The diphenyl sulfide derivative and application thereof that 2- replaces | 广东东阳光药业有限公司 | 2019-01-01 | — | — | CN | disclosed |