Famoxadone

Famoxadone

SCHEMBL28267474

CC1(c2ccc(Oc3ccccc3)cc2)OC(=O)N(Nc2ccccc2)C1=O.Cc1cc(O)no1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
GAA P10253 2/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 3/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP1 P03956 1/20 0.33
ADAM17 P78536 1/20 0.33
RAF1 P04049 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
RAB9A P51151 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Famoxadone SCHEMBL63351 0.87 MMP2 (0.42) LMNATSHRALDH1A1MMP2MMP9
Famoxadone SCHEMBL673443 0.87 MMP2 (0.42) LMNATSHRALDH1A1MMP2MMP9
Famoxadone SCHEMBL14128616 0.87 MMP2 (0.42) LMNATSHRALDH1A1MMP2MMP9
Famoxadone SCHEMBL17293878 0.85 MMP2 (0.41) LMNATSHRALDH1A1MMP2MMP9
Famoxadone SCHEMBL28139781 0.84 MMP1 (0.40) MMP2MMP9MMP1ADAM17RAB9A
Famoxadone SCHEMBL6060933 0.82 MMP2 (0.36) LMNATSHRMMP2MMP9MMP1
Famoxadone SCHEMBL27502240 0.81 MMP2 (0.38) ALDH1A1MMP2MMP9MMP1ADAM17
SCHEMBL9370594 0.81 PGR (0.39) LMNATSHRMMP2MMP9MMP1
SCHEMBL27339346 0.81 PGR (0.39) LMNATSHRMMP2MMP9MMP1
SCHEMBL7761159 0.79 LMNA (0.39) LMNATSHRALDH1A1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109169678-A Bactericide and composition thereof 侨昌现代农业有限公司 2019-01-11 CN disclosed