Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | SDHB | P21912 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30505019 | 0.74 | KDM5B (0.41) | LOXL2BPTFMAPK1KDM5B | |
| SCHEMBL5022939 | 0.73 | CCR1 (0.44) | LMNASMN1; SMN2BPTFSDHBRAB9A | |
| SCHEMBL28269314 | 0.71 | NPC1 (0.41) | LMNASMN1; SMN2BPTFSDHBRAB9A | |
| SCHEMBL5017672 | 0.69 | BPTF (0.47) | LMNASMN1; SMN2BPTFSDHBRAB9A | |
| SCHEMBL10519534 | 0.68 | NOS3 (0.50) | LMNASMN1; SMN2BPTFSDHBRAB9A | |
| SCHEMBL25435575 | 0.68 | LOXL2 (0.36) | LOXL2CYP2C9CYP2C19CYP2E1CYP2A6 | |
| SCHEMBL21020091 | 0.67 | KDM4E (0.67) | CYP2C9CYP2C19LMNASMN1; SMN2SDHB | |
| SCHEMBL8597269 | 0.66 | LMNA (0.42) | LMNASMN1; SMN2BPTFSDHBRAB9A | |
| SCHEMBL5017675 | 0.66 | LMNA (0.50) | CYP2C9CYP2C19CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL20092109 | 0.66 | SYK (0.48) | LOXL2CYP2C9CYP2C19CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118946560-A | POLO-like kinase 4 (PLK 4) inhibitors, pharmaceutical compositions, methods for their preparation and uses | 修复治疗公司 | 2024-11-12 | — | — | CN | disclosed |