SCHEMBL28274223

SCHEMBL28274223

CNc1ccc(S(=O)(=O)C2CNCCO2)cc1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.40
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28433779 0.84 HTR6 (0.39) CA12CA2CA1CA9
SCHEMBL5821011 0.81 MMP2 (0.33) CA2CA1
SCHEMBL27828787 0.81 DRD2 (0.40) CA12CA2CA1CA9
SCHEMBL10781545 0.81 MAPT (0.44)
SCHEMBL14775611 0.81 HTR6 (0.37) CA12CA2CA1CA9
SCHEMBL4771959 0.81 GLA (0.35) CA2
SCHEMBL6422590 0.80 SLC6A2 (0.38)
SCHEMBL28246223 0.78 CTSC (0.39) CA12CA2CA1CA9
SCHEMBL3866888 0.78 DRD2 (0.34)
SCHEMBL28425430 0.77 CA2 (0.40) CA12CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311882-A adenine derivatives as protein kinase inhibitors BCI制药公司 2019-02-05 CN disclosed