Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LGMN | Q99538 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498780 | 0.75 | CALM1 (0.55) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL13650811 | 0.73 | HPGD (0.55) | ALDH1A1GAAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL5790172 | 0.73 | DRD1 (0.51) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL1964226 | 0.72 | MAPT (0.51) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL4822657 | 0.71 | CTSB (0.56) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL5791945 | 0.71 | LMNA (0.64) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL11862853 | 0.71 | HTT (0.56) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL30443433 | 0.70 | KEAP1 (0.64) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL127620 | 0.70 | KEAP1 (0.64) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL3217857 | 0.69 | HPGD (0.59) | ALDH1A1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-A | A kind of highly selective 4-(4- aminophenyl) morpholine -3- ketone synthetic method | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-109384738-A | A kind of preparation method of high-purity 4- (4- aminophenyl) morpholine -3- ketone | 新发药业有限公司 | 2019-02-26 | — | — | CN | disclosed |