SCHEMBL28277461

SCHEMBL28277461

CC(C)(C)C(=O)Nc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.73
MAPT P10636 11/20 0.68
ALDH1A1 P00352 6/20 0.68
HPGD P15428 5/20 0.68
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
HTT P42858 2/20 0.68
MAPK1 P28482 1/20 0.68
LMNA P02545 1/20 0.65
POLB P06746 1/20 0.63
CASP3 P42574 1/20 0.62
SENP7 Q9BQF6 1/20 0.62
GAA P10253 4/20 0.62
RAB9A P51151 1/20 0.62
GFER P55789 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
PDK1 Q15118 2/20 0.56
PDK2 Q15119 2/20 0.56
PDK3 Q15120 2/20 0.56
PDK4 Q16654 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83110 0.92 L3MBTL1 (0.78) L3MBTL1MAPTALDH1A1HPGDMEN1
SCHEMBL1978046 0.87 MAPT (0.66) L3MBTL1MAPTALDH1A1HPGDMEN1
SCHEMBL384054 0.86 L3MBTL1 (0.69) L3MBTL1MAPTALDH1A1HPGDMEN1
SCHEMBL7733701 0.85 L3MBTL1 (1.00) L3MBTL1MAPTALDH1A1HPGDMEN1
SCHEMBL29037529 0.85 L3MBTL1 (0.73) L3MBTL1MAPTALDH1A1MEN1KMT2A
SCHEMBL14033573 0.81 LMNA (0.76) L3MBTL1MAPTALDH1A1HPGDMEN1
SCHEMBL11652119 0.81 MAPT (1.00) L3MBTL1MAPTALDH1A1HPGDMEN1
SCHEMBL14253966 0.80 PDK1 (0.70) L3MBTL1MAPTALDH1A1HPGDMEN1
SCHEMBL19501628 0.80 NPSR1 (0.63) L3MBTL1MAPTMEN1KMT2AHTT
SCHEMBL14849461 0.79 PDK1 (0.63) L3MBTL1MAPTALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025102500-A1 NITRILE RUBBER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油天然气股份有限公司 2025-05-22 WO claimed
CN-119978233-A Preparation method of nitrile rubber with improved thermo-oxidative aging resistance 中国石油天然气股份有限公司 2025-05-13 CN claimed
CN-119978235-A Nitrile rubber and preparation method and application thereof 中国石油天然气股份有限公司 2025-05-13 CN claimed
CN-109438273-A A kind of preparation method of rubber antioxidant N- (4- aniiinophenyl) pivaloyl amine 连云港锐巴化工有限公司 2019-03-08 CN claimed
WO-2025102500-A1 NITRILE RUBBER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油天然气股份有限公司 2025-05-22 WO disclosed
CN-119978233-A Preparation method of nitrile rubber with improved thermo-oxidative aging resistance 中国石油天然气股份有限公司 2025-05-13 CN disclosed
CN-119978235-A Nitrile rubber and preparation method and application thereof 中国石油天然气股份有限公司 2025-05-13 CN disclosed
CN-109438273-A A kind of preparation method of rubber antioxidant N- (4- aniiinophenyl) pivaloyl amine 连云港锐巴化工有限公司 2019-03-08 CN disclosed
CN-109438273-A A kind of preparation method of rubber antioxidant N- (4- aniiinophenyl) pivaloyl amine 连云港锐巴化工有限公司 2019-03-08 CN disclosed
CN-109438273-A A kind of preparation method of rubber antioxidant N- (4- aniiinophenyl) pivaloyl amine 连云港锐巴化工有限公司 2019-03-08 CN disclosed