SCHEMBL2827920

SCHEMBL2827920

NC12CCC(O)(CC1)CC2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.32
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL13735171 0.96 PNMT (0.31) PNMT
SCHEMBL13085377 0.79
SCHEMBL1903771 0.78 PNMT (0.40) PNMT
Hydrochloric Acid SCHEMBL19747006 0.76
Hydrochloric Acid SCHEMBL13733142 0.76 PKM (0.37) PKM
Hydrochloric Acid SCHEMBL2875147 0.74 PNMT (0.38) PNMT
SCHEMBL20221206 0.67 PKM (0.40) PKM
SCHEMBL19850684 0.67 PNMT (0.35) PNMT
SCHEMBL319529 0.65
SCHEMBL16039063 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552787-B2 Quinazoline compound MEDSHINE DISCOVERY INC. (CN) 2026-02-17 US disclosed
US-20250361399-A1 FLUORESCENT DYES WITH LARGE STOKES SHIFT ROCHE MOLECULAR SYSTEMS INC (US) 2025-11-27 US disclosed
EP-4547757-A2 FLUORESCENT DYES WITH LARGE STOKES SHIFT F. Hoffmann-La Roche AG (CH) 2025-05-07 EP disclosed
EP-3971177-B1 AMINOPYRIDINE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS NOVARTIS AG (CH) 2024-06-26 EP disclosed
CN-113453764-B 7H-pyrrolo [2,3-d ] pyrimidin-4-amine derivatives 大鹏药品工业株式会社 2024-04-16 CN disclosed
EP-3583105-B1 PYRROLO [1,2-B]PYRIDAZINE DERIVATIVES GILEAD SCIENCES INC (US) 2024-02-07 EP disclosed
WO-2024002924-A2 FLUORESCENT DYES WITH LARGE STOKES SHIFT F. HOFFMANN-LA ROCHE AG (CH) 2024-01-04 WO disclosed
US-11786534-B2 Substituted pyrrolo[2,3-d]pyrimidines as EGFR inhibitors TAIHO PHARMACEUTICAL CO., LTD. (JP) 2023-10-17 US disclosed
US-20230265090-A1 QUINAZOLINE COMPOUND MEDSHINE DISCOVERY INC. (CN) 2023-08-24 US disclosed
US-20230265090-A1 QUINAZOLINE COMPOUND MEDSHINE DISCOVERY INC. (CN) 2023-08-24 US disclosed
WO-2015019325-A1 BENZIMIDAZOLYL-METHYL UREA DERIVATIVES AS ALX RECEPTOR AGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2015-02-12 WO disclosed
US-20140296233-A1 HETEROARYL COMPOUNDS AND USES THEREOF SANOFI (FR) 2014-10-02 US disclosed
WO-2014144737-A1 HETEROARYL COMPOUNDS AND USES THEREOF CELGENE AVILOMICS RESEARCH, INC. (US) 2014-09-18 WO disclosed
US-8507493-B2 Amide and amidine derivatives and uses thereof ABBVIE INC. (US) 2013-08-13 US disclosed
WO-2010123838-A2 NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-10-28 WO disclosed
EP-2243479-A2 Novel amide and amidine derivates and uses thereof Abbott Laboratories (US) 2010-10-27 EP disclosed
US-20100267738-A1 NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-10-21 US disclosed
US-7560569-B2 (2S,4S)-1-[[(4-carbamoylbicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile, for treating type II diabetes; increase glucagon-like peptide activity KYORIN PHARMACEUTICAL CO., LTD (JP) 2009-07-14 US disclosed
US-20070265320-A1 Bicycloamide Derivative KYORIN PHARMACEUTICAL CO., LTD (JP) 2007-11-15 US disclosed
EP-1717225-A1 BICYCLIC AMIDE DERIVATIVES Kyorin Pharmaceutical Co., Ltd. (JP) 2006-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267738-A1 NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF HSD11B2, HSD11B1, HSD17B2 PNMT 1078/4885PKM 1857/4885
US-20230265090-A1 QUINAZOLINE COMPOUND ABCG2, CYP3A7, ABL1 PNMT 2809/4885PKM 2336/4885
US-20140296233-A1 HETEROARYL COMPOUNDS AND USES THEREOF ABCG2, CYP3A43, CYP3A5 PNMT 2016/4885PKM 2625/4885
US-20070265320-A1 Bicycloamide Derivative DPP4, DPP7, DPP9 PNMT 3480/4885PKM 1468/4885
US-12552787-B2 Quinazoline compound SLC9A3, CLIC1, NHERF1 PNMT 3880/4885PKM 2711/4885
US-11786534-B2 Substituted pyrrolo[2,3-d]pyrimidines as EGFR inhibitors EGFR, ERBB2, ERBB3 PNMT 3277/4885PKM 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.