Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 7/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28412210 | 0.80 | HPGD (0.36) | HPGDDAOMAPK1METGAA | |
| SCHEMBL28287426 | 0.75 | HPGD (0.60) | HPGDDAOMAPK1 | |
| SCHEMBL7711012 | 0.75 | UPP1 (0.41) | HPGDDAOMAPK1TK2 | |
| SCHEMBL28288700 | 0.71 | LMNA (0.44) | ADORA2AADORA2BLMNA | |
| SCHEMBL15850325 | 0.70 | MET (0.58) | HPGDDAOMET | |
| SCHEMBL3953282 | 0.67 | ALDH1A1 (0.50) | LMNAGAA | |
| SCHEMBL28417123 | 0.67 | ADORA2B (0.41) | HPGDADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9880650 | 0.66 | ERCC1 (0.49) | CRBNADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28482699 | 0.64 | DAO (0.51) | HPGDDAOMAPK1 | |
| SCHEMBL16248 | 0.64 | MAPK1 (0.47) | HPGDCRBNDAOMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651267-B | Method for preparing 5-sulfur/selenium modified uracil derivative | 中国科学院化学研究所 | 2020-05-19 | — | — | CN | disclosed |
| CN-109651267-A | Prepare 5- sulphur/selenium modification uracil derivative method | 中国科学院化学研究所 | 2019-04-19 | — | — | CN | disclosed |