SCHEMBL28289735

SCHEMBL28289735

COC(=O)N1C=CSC=C1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.33
TSHR P16473 1/20 0.32
LPO P22079 2/20 0.31
P2RX4 Q99571 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9753105 0.73 TSHR (0.33) BCHETSHRLPOP2RX4
SCHEMBL5344293 0.71 MAPK1 (0.38) TSHRLPOP2RX4
SCHEMBL3262997 0.69
SCHEMBL1649446 0.67 TSHR (0.33) TSHR
SCHEMBL7641213 0.65 TSHR (0.31) TSHRLPO
SCHEMBL30491883 0.64
SCHEMBL568621 0.57
Methane SCHEMBL11818903 0.55 LPO (0.38) BCHETSHRLPOP2RX4
SCHEMBL5548370 0.55
SCHEMBL29211812 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109562113-A Spirocyclo-rongeur for target protein degradation C4医药公司 2019-04-02 CN disclosed