SCHEMBL28290008

SCHEMBL28290008

NCc1ccccc1NS(=O)(=O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
RECQL P46063 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TSHR P16473 2/20 0.53
POLB P06746 1/20 0.53
HTR6 P50406 2/20 0.51
KEAP1 Q14145 2/20 0.50
IL1RN P18510 1/20 0.50
ERAP1 Q9NZ08 1/20 0.50
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
PKM P14618 1/20 0.47
G6PD P11413 1/20 0.46
NFKBIA P25963 1/20 0.46
AGTR1 P30556 1/20 0.46
METAP2 P50579 1/20 0.46
METAP1 P53582 1/20 0.46
GLO1 Q04760 1/20 0.46
PAX8 Q06710 1/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL7208092 0.85 HTR6 (0.56) ALDH1A1RECQLSMN1; SMN2TSHRPOLB
SCHEMBL10272404 0.84 ALDH1A1 (0.71) ALDH1A1RECQLSMN1; SMN2TSHRPOLB
SCHEMBL12050285 0.82 RECQL (0.57) ALDH1A1RECQLSMN1; SMN2TSHRPOLB
SCHEMBL13416386 0.81 MEN1 (0.61) ALDH1A1RECQLSMN1; SMN2TSHRPOLB
SCHEMBL2067538 0.80 ALDH1A1 (0.68) ALDH1A1RECQLSMN1; SMN2POLBKEAP1
Hydrochloric Acid SCHEMBL28787345 0.80 KEAP1 (0.51) TSHRHTR6KEAP1KMT2AMEN1
SCHEMBL10438570 0.79 ALDH1A1 (0.57) ALDH1A1RECQLSMN1; SMN2TSHRPOLB
SCHEMBL5205026 0.79 ALDH1A1 (0.58) ALDH1A1RECQLSMN1; SMN2TSHRPOLB
SCHEMBL28655832 0.78 KEAP1 (0.50) ALDH1A1RECQLSMN1; SMN2TSHRPOLB
SCHEMBL1691697 0.78 ALDH1A1 (0.53) ALDH1A1RECQLSMN1; SMN2TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109574863-A A kind of synthetic method of -4 ' of 2- amino-fluoro- benzophenone 安徽省庆云医药股份有限公司 2019-04-05 CN disclosed