Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290008 | 0.85 | ALDH1A1 (0.53) | HTR6ALDH1A1POLBTSHRRECQL | |
| Hydrochloric Acid SCHEMBL27828051 | 0.83 | ALDH1A1 (0.51) | HTR6ALDH1A1POLBTSHRRECQL | |
| SCHEMBL10438570 | 0.82 | ALDH1A1 (0.57) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 | |
| SCHEMBL4774366 | 0.80 | PRMT1 (0.50) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 | |
| SCHEMBL10272404 | 0.80 | ALDH1A1 (0.71) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 | |
| SCHEMBL7211586 | 0.79 | HTR6 (0.56) | HTR6ALDH1A1POLBTSHRRECQL | |
| SCHEMBL3897238 | 0.79 | KEAP1 (0.55) | ALDH1A1POLBTSHRKEAP1SLC16A3 | |
| SCHEMBL6900797 | 0.79 | METAP2 (0.56) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 | |
| SCHEMBL12050285 | 0.78 | RECQL (0.57) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 | |
| SCHEMBL27478563 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152857-C | Phenylsulfonamide-phenylethylamines useful as dopamine receptors | �������Ŷ���Լ��������˾ | 2004-06-09 | — | — | CN | claimed |
| EP-1077935-B1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | UPJOHN CO (US) | 2003-10-29 | — | — | EP | claimed |
| EP-1077935-B1 | PHENYLSULFONAMIDE-PHENYLETHYLAMINES USEFUL AS DOPAMINE RECEPTORS | UPJOHN CO (US) | 2003-10-29 | — | — | EP | disclosed |