Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149485 | 0.76 | LMNA (0.33) | SMN1; SMN2POLB | |
| SCHEMBL2574861 | 0.76 | ESR1 (0.44) | ESR1ARESR2 | |
| SCHEMBL28205756 | 0.76 | KCNN4 (0.36) | KIF11SMN1; SMN2POLB | |
| SCHEMBL8486558 | 0.74 | — | — | |
| SCHEMBL11024100 | 0.74 | KIF11 (0.38) | KIF11SMN1; SMN2 | |
| SCHEMBL27487116 | 0.73 | CFTR (0.41) | POLB | |
| SCHEMBL11026542 | 0.73 | NPC1 (0.35) | SMN1; SMN2 | |
| SCHEMBL4689119 | 0.72 | MEN1 (0.46) | SMN1; SMN2 | |
| SCHEMBL28113310 | 0.71 | ALDH1A1 (0.47) | — | |
| SCHEMBL27876225 | 0.71 | KIF11 (0.45) | KIF11SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661392-A | For treating the mitochondrial inhibitors of proliferative disorder | 巴斯利尔药物国际股份公司 | 2019-04-19 | — | — | CN | disclosed |