Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678160 | 0.81 | MTNR1A (0.58) | IDO1MTNR1AMTNR1BKDM4EMAPT | |
| SCHEMBL28929782 | 0.77 | MTNR1A (0.57) | MTNR1AMTNR1BKDM4EMAPTKMT2A | |
| SCHEMBL28672705 | 0.74 | LOXL2 (0.58) | MTNR1AMTNR1BKDM4EMAPTHDAC6 | |
| SCHEMBL27551544 | 0.73 | KDM4E (0.36) | KDM4EMAPTKMT2AMEN1NPC1 | |
| SCHEMBL28994911 | 0.72 | EHMT2 (0.41) | MTNR1AMTNR1BPOLB | |
| SCHEMBL27491895 | 0.69 | DAO (0.43) | MTNR1AMTNR1BGPR84 | |
| SCHEMBL27965811 | 0.69 | PARP1 (0.40) | MTNR1AMTNR1BPOLBGPR84TDP1 | |
| SCHEMBL28880746 | 0.69 | PTGS2 (0.45) | IDO1MTNR1AMTNR1BTUBB1 | |
| SCHEMBL27778367 | 0.69 | RHEB (0.36) | GPR17 | |
| SCHEMBL27906754 | 0.68 | DAO (0.44) | MTNR1AMTNR1BKDM4EMAPTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |