Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293148 | 0.89 | GHSR (0.39) | GHSRGPR84MTNR1AMTNR1BMAPT | |
| SCHEMBL28038999 | 0.86 | NR3C1 (0.39) | MTNR1AMTNR1BIDH1LOXL2HRH3 | |
| SCHEMBL28072238 | 0.82 | LOXL2 (0.54) | MTNR1AMTNR1BMAPTLOXL2HRH3 | |
| SCHEMBL28672705 | 0.80 | LOXL2 (0.58) | GHSRMTNR1AMTNR1BMAPTMAPK1 | |
| SCHEMBL28038688 | 0.80 | KDM4E (0.40) | GPR84MTNR1AMTNR1BMAPTLOXL2 | |
| SCHEMBL27650372 | 0.79 | CYP19A1 (0.39) | MTNR1AMTNR1BLOXL2HRH3 | |
| SCHEMBL27697394 | 0.79 | PCSK9 (0.42) | GHSRMTNR1AMTNR1BMAPTNR3C1 | |
| SCHEMBL27613737 | 0.79 | LOXL2 (0.54) | MTNR1AMTNR1BIDH1MAPTLOXL2 | |
| SCHEMBL27648957 | 0.79 | CYP2A6 (0.42) | MTNR1AMTNR1BMAPTLOXL2HRH3 | |
| SCHEMBL28819115 | 0.77 | MTNR1A (0.43) | MTNR1AMTNR1BHRH3KIF11HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |