Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294624 | 0.83 | POLB (0.40) | NPSR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL14466870 | 0.80 | LMNA (0.40) | NPSR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL15118626 | 0.78 | LMNA (0.41) | NPSR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL28291723 | 0.77 | LMNA (0.50) | KMT2ALMNAMEN1HSD11B1GAA | |
| SCHEMBL14466869 | 0.76 | ALDH1A1 (0.39) | NPSR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL28291724 | 0.75 | HSD11B1 (0.44) | MAPTKMT2AMEN1HSD11B1GAA | |
| SCHEMBL11913028 | 0.74 | ALDH1A1 (0.40) | NPSR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL6818883 | 0.74 | KMT2A (0.43) | NPSR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL29660673 | 0.74 | ALDH1A1 (0.40) | NPSR1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL15877470 | 0.72 | CYP2C19 (0.38) | MAPTKMT2ALMNAMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608390-B | Synthesis method of chiral quaternary carbon pyridine beta-hydroxy ester compound | 温州大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-109608390-A | A kind of synthetic method of chirality quaternary carbon pyridines β hydroxyl esters compound | 温州大学 | 2019-04-12 | — | — | CN | disclosed |