Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19693406 | 0.74 | LMNA (0.49) | PDK2ALDH1A1MAPT | |
| SCHEMBL9832263 | 0.73 | PGR (0.33) | PGRPDK2PDK4ALDH1A1MAPT | |
| SCHEMBL28294129 | 0.72 | MAOB (0.34) | — | |
| SCHEMBL9833677 | 0.70 | PGR (0.32) | PGRALDH1A1MAPT | |
| SCHEMBL10151655 | 0.69 | AKR1B1 (0.42) | PDK2PDK4ALDH1A1MAPT | |
| SCHEMBL5536803 | 0.67 | PDK2 (0.55) | PGRPDK2PDK4 | |
| SCHEMBL9833671 | 0.65 | AURKA (0.40) | ALDH1A1MAPT | |
| SCHEMBL6072306 | 0.63 | PGR (0.58) | PGRPDK2PDK4 | |
| SCHEMBL9376592 | 0.60 | PGR (0.51) | PGRALDH1A1MAPT | |
| SCHEMBL14188959 | 0.59 | MMP2 (0.38) | PDK2PDK4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325533-A | INHIBITORS OF THE MENIN-MLL INTERACTION | 生命医药有限责任公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109743875-A | The inhibitor of MENIN-MLL interaction | 生命医药公司 | 2019-05-10 | — | — | CN | disclosed |