Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788379 | 0.75 | PGR (0.46) | MAOB | |
| SCHEMBL28294093 | 0.72 | PGR (0.34) | — | |
| SCHEMBL19693406 | 0.68 | LMNA (0.49) | — | |
| SCHEMBL28124763 | 0.67 | EIF2AK2 (0.51) | MAOB | |
| SCHEMBL9832263 | 0.65 | PGR (0.33) | — | |
| SCHEMBL9833677 | 0.65 | PGR (0.32) | — | |
| SCHEMBL12051255 | 0.65 | ESR2 (0.38) | — | |
| SCHEMBL28835938 | 0.62 | SMN1; SMN2 (0.40) | MAOB | |
| SCHEMBL11392894 | 0.62 | CA2 (0.39) | MAOB | |
| SCHEMBL10151655 | 0.61 | AKR1B1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325533-A | INHIBITORS OF THE MENIN-MLL INTERACTION | 生命医药有限责任公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109743875-A | The inhibitor of MENIN-MLL interaction | 生命医药公司 | 2019-05-10 | — | — | CN | disclosed |