Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138321 | 0.76 | ATAD2 (0.50) | PGRPDK2PDK4ATAD2 | |
| SCHEMBL9833677 | 0.76 | PGR (0.32) | PGRALDH1A1MAPTATAD2 | |
| SCHEMBL28294093 | 0.73 | PGR (0.34) | PGRALDH1A1MAPTPDK2PDK4 | |
| SCHEMBL9833671 | 0.70 | AURKA (0.40) | ALDH1A1MAPT | |
| SCHEMBL9833981 | 0.69 | MAPK14 (0.33) | PGRALDH1A1MAPTPDK2PDK4 | |
| SCHEMBL9832258 | 0.68 | PGR (0.47) | PGRALDH1A1 | |
| SCHEMBL19693406 | 0.67 | LMNA (0.49) | ALDH1A1MAPTPDK2 | |
| SCHEMBL28294129 | 0.65 | MAOB (0.34) | — | |
| SCHEMBL9379048 | 0.64 | RARB (0.43) | PGR | |
| SCHEMBL9598945 | 0.64 | PGR (0.50) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161632-B1 | PYRROLO-BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND INTERMEDIATES | Roche Diagnostics GmbH (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4963686-A | INTERMEDIATES FOR INOTROPIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-16 | — | — | US | disclosed |