Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195988 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTPOLBGPR55GAA | |
| SCHEMBL1708608 | 0.77 | POLB (0.38) | ALDH1A1MAPTPOLBGPR55GAA | |
| SCHEMBL5552171 | 0.76 | KAT6A (0.40) | ALDH1A1MAPTPOLBGPR55THRB | |
| SCHEMBL28846878 | 0.75 | ALDH1A1 (0.35) | ALDH1A1MAPTPOLBGAAKDM4E | |
| SCHEMBL16637746 | 0.75 | POLB (0.33) | ALDH1A1MAPTPOLBGPR55GAA | |
| SCHEMBL12470458 | 0.74 | KDM4E (0.36) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL28823865 | 0.73 | RAPGEF4 (0.38) | ALDH1A1MAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL28029394 | 0.73 | MAPT (0.41) | ALDH1A1MAPTPOLBGAATHRB | |
| SCHEMBL29288404 | 0.71 | LMNA (0.35) | ALDH1A1MAPTPOLBKDM4ETSHR | |
| SCHEMBL9425246 | 0.70 | MEP1B (0.38) | ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641852-A | Sulfonamides as GPR 40-and GPR 120-agonists | 东佩制药股份公司 | 2019-04-16 | — | — | CN | disclosed |