Phencyclidine

Phencyclidine

SCHEMBL28296317

CNC.c1ccc(C2(N3CCCCC3)CCCCC2)cc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 5/20 0.86
GRIN2A Q12879 5/20 0.86
GRIN2B Q13224 4/20 0.86
SIGMAR1 Q99720 3/20 0.86
PRCP P42785 3/20 0.86
GRIN2D O15399 1/20 0.86
GRIN3B O60391 1/20 0.86
CYP2B6 P20813 1/20 0.86
SLC6A2 P23975 1/20 0.86
SLC6A4 P31645 1/20 0.86
SLC6A3 Q01959 1/20 0.86
KCNH2 Q12809 1/20 0.86
GRIN2C Q14957 1/20 0.86
GRIN3A Q8TCU5 1/20 0.86
OPRM1 P35372 3/20 0.83
OPRD1 P41143 1/20 0.83
OPRL1 P41146 2/20 0.49
SLC6A9 P48067 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phencyclidine SCHEMBL42022 0.93 SIGMAR1 (1.00) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
Rolicyclidine SCHEMBL517928 0.93 SIGMAR1 (1.00) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
Phencyclidine SCHEMBL17008793 0.93 SIGMAR1 (1.00) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
SCHEMBL9153279 0.93 SIGMAR1 (1.00) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
Phencyclidine SCHEMBL21777 0.91 OPRM1 (1.00) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
Phencyclidine SCHEMBL5166553 0.91 SIGMAR1 (0.96) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
Phencyclidine SCHEMBL9431514 0.89 SIGMAR1 (0.92) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
SCHEMBL3407261 0.89 GRIN1 (0.92) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
SCHEMBL28282384 0.87 GRIN1 (0.88) GRIN1GRIN2AGRIN2BSIGMAR1PRCP
Phencyclidine SCHEMBL28127392 0.86 SIGMAR1 (0.80) GRIN1GRIN2AGRIN2BSIGMAR1PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721739-A Three core zinc of polymer benzene tetracarboxylic acid and synthetic method 桂林理工大学 2019-05-07 CN claimed