Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658053 | 0.89 | LMNA (0.54) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Benzene SCHEMBL28330086 | 0.88 | LMNA (0.53) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL76327 | 0.88 | LMNA (0.53) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Cadaverine Tartrate SCHEMBL28736232 | 0.87 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Cadaverine Tartrate SCHEMBL28777306 | 0.85 | HPGD (0.46) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Sulfur Dioxide SCHEMBL28176580 | 0.84 | LMNA (0.50) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Sulfuric Acid SCHEMBL5004844 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL460030 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29276978 | 0.83 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL8015558 | 0.81 | MEN1 (0.48) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734617-A | A kind of method for splitting replacing aromatic ring phenylglycine aliphatic alcohol ester | 华东理工大学 | 2019-05-10 | — | — | CN | disclosed |