Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460030 | 0.96 | ALDH1A1 (0.49) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| SCHEMBL28161510 | 0.93 | ALDH1A1 (0.47) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| SCHEMBL658053 | 0.93 | LMNA (0.54) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| Benzene SCHEMBL28330086 | 0.91 | LMNA (0.53) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL76327 | 0.91 | LMNA (0.53) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| Sulfur Dioxide SCHEMBL28176580 | 0.87 | LMNA (0.50) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| Sulfuric Acid SCHEMBL28065986 | 0.85 | POLB (0.55) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8015558 | 0.84 | MEN1 (0.48) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| Cadaverine Tartrate SCHEMBL28296884 | 0.83 | MAPT (0.47) | ALDH1A1RAB9ALMNAMAPTMEN1 | |
| Nitric Acid SCHEMBL27965091 | 0.83 | ALDH1A1 (0.47) | ALDH1A1RAB9ALMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103805672-B | A kind of enzyme process is prepared the technique of ampicillin | NORTH CHINA PHARMACEUTICAL GROUP XIANTAI PHARMACEUTICAL CO., LTD. (CN) | 2016-05-25 | — | — | CN | claimed |
| CN-108822131-A | The method of ampicillin is separated from the reaction product of enzyme process preparation ampicillin | 国药集团威奇达药业有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-108822133-A | The method that cefalexin is separated in the reaction product of cefalexin is prepared from enzyme process | 国药集团威奇达药业有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-106957236-A | A kind of preparation method of Phenylglycine methyl ester methyl-hydrogen-sulfate monomethyl-sulfate salt | 浙江昂利康制药股份有限公司 | 2017-07-18 | — | — | CN | disclosed |
| CN-103805672-B | A kind of enzyme process is prepared the technique of ampicillin | NORTH CHINA PHARMACEUTICAL GROUP XIANTAI PHARMACEUTICAL CO., LTD. (CN) | 2016-05-25 | — | — | CN | disclosed |
| EP-1931619-B1 | METHANESULPHONIC ACID SALT OF DIHYDROPHENYLGLYCINE METHYL ESTER OR OF PHENYLGLYCINE METHYL ESTER | DSM SINOCHEM PHARM NL BV (NL) | 2015-06-24 | — | — | EP | disclosed |
| US-20080249329-A1 | Process For Esterification Of An Organic Acid | DSM IP ASSETS B.V. (NL) | 2008-10-09 | — | — | US | disclosed |