Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28198723 | 0.75 | ACHE (0.38) | ACHEGDASLC6A5MAPTERAP1 | |
| SCHEMBL26778859 | 0.74 | LMNA (0.37) | ACHEGDASLC6A5MAPTPRKACA | |
| SCHEMBL30905810 | 0.74 | FFAR2 (0.44) | ACHEGDASLC6A5MAPTPRKACA | |
| SCHEMBL30905809 | 0.74 | LMNA (0.37) | ACHEGDASLC6A5MAPTPRKACA | |
| SCHEMBL26779045 | 0.72 | SLC6A5 (0.42) | ACHEGDASLC6A5MAPTAKT2 | |
| SCHEMBL29385750 | 0.71 | ERAP1 (0.61) | ACHEGDASLC6A5MAPTERAP1 | |
| SCHEMBL48258 | 0.71 | ERAP1 (0.61) | ACHEGDASLC6A5MAPTERAP1 | |
| SCHEMBL26779024 | 0.70 | SLC6A5 (0.40) | ACHEGDASLC6A5MAPTPRKACA | |
| SCHEMBL27051002 | 0.70 | SLC6A5 (0.43) | ACHEGDASLC6A5MAPT | |
| SCHEMBL12779523 | 0.69 | GDA (0.42) | ACHEGDASLC6A5MAPTERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |