Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26779045 | 0.84 | SLC6A5 (0.42) | SLC6A5NPC1RAB9AACHEGDA | |
| SCHEMBL26778638 | 0.80 | ADORA3 (0.55) | NPC1RAB9ASMN1; SMN2KDRBRAF | |
| SCHEMBL26779026 | 0.74 | CDK1 (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL26798432 | 0.74 | MAPT (0.51) | NPC1RAB9AALDH1A1KDRPOLB | |
| SCHEMBL26778859 | 0.72 | LMNA (0.37) | SLC6A5NPC1RAB9AACHEGDA | |
| SCHEMBL30905810 | 0.72 | FFAR2 (0.44) | SLC6A5ACHEGDAALDH1A1AKT2 | |
| SCHEMBL30905809 | 0.72 | LMNA (0.37) | SLC6A5NPC1RAB9AACHEGDA | |
| SCHEMBL28299580 | 0.70 | ACHE (0.38) | SLC6A5ACHEGDAAKT2BRD4 | |
| SCHEMBL28198723 | 0.70 | ACHE (0.38) | SLC6A5ACHEGDAAKT2BRD4 | |
| SCHEMBL3918824 | 0.70 | ENPP1 (0.42) | SLC6A5SMN1; SMN2ALDH1A1BRD4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |