Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270935 | 0.78 | ALDH1A1 (0.77) | NPC1RAB9APOLBKMT2AALDH1A1 | |
| SCHEMBL29356619 | 0.78 | ALDH1A1 (0.77) | NPC1RAB9APOLBKMT2AALDH1A1 | |
| SCHEMBL29246641 | 0.78 | GAA (0.60) | NPC1RAB9AMTNR1AMTNR1BNQO2 | |
| SCHEMBL5724399 | 0.76 | NPC1 (0.64) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL25280066 | 0.74 | HTR2A (0.61) | POLBKMT2A | |
| SCHEMBL5726019 | 0.74 | ALDH1A1 (0.63) | NPC1RAB9AMTNR1AMTNR1BKMT2A | |
| SCHEMBL7274134 | 0.74 | NPC1 (0.85) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL29111414 | 0.73 | MTNR1A (0.65) | NPC1RAB9AMTNR1AMTNR1BNQO2 | |
| SCHEMBL9312655 | 0.73 | NPC1 (1.00) | NPC1RAB9APOLBKMT2AMAPT | |
| SCHEMBL11716101 | 0.73 | MTNR1B (0.68) | NPC1RAB9AMTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540596-B | A kind of compound 5, the preparation method of 6- dihydroxy indole quinoline and its halogen acid salt | 烟台六谛医药科技有限公司 | 2019-06-14 | — | — | CN | disclosed |